Mapping the Cycle

The Big Picture: Mapping Mutants to Conformations to Biochemical states

 

Below is a reasonably complete summary of the genetic information regarding ÆWrinkle, E531Q, P536R and R562H. Conventions are as follows:
  • Arrowheads indicate genetic suppression
  • Arrows that go to a shape perimeter apply to all mutants within the shape
  • Arrows that go to a specific mutation apply only to that mutation (in all cases, this is currently due to lack of data, NOT because any given mutant is KNOWN NOT TO SUPPRESS. Such data are being gathered at present)
  • Gray ovals indicate other archetypes
  • the Blue lists are suppressors that have as yet been identified only for one mutant
NavTable Comments Help!


Bruce Patterson
http://research.biology.arizona.edu/myosin