E586K [F11]
Suppresses
WHERE: E586K is in the alpha helix running perpendicular to the screen in F11.
WHAT: E586K was one of the original cold-sensitive mutants. It has also been found spontaneously as a suppressor of P536R, E531Q and R562H. These latter 3 are in the actin-binding region of myosin and have defects in their actin interaction properties.
FRIENDS & RELATIONS: By its ability to suppress the actin-binding region mutants, E586K is related to many of the other suppressors isolated by Erik Misner:
Image: E586K can be found in the ActBind mirror.
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