What's THIS? Nothing less than the sum total of everything we know about the relatedness of Dictyostelium myosin genetics! Boxes are used to group related mutants. Relatedness is on the basis of the ability of all mutants in a group to suppress or be suppressed by another mutant(s). Sometimes a subset of such a family is known to have further suppression/suppressability abilities in common; this is designated by a box-within-a-box. Colors of boxes are largely just to emphasize similarities and differences, though I have tried to make similar colors reflect similarities in behavior. Arrowheads indicate suppression, i.e. the mutations in the RED box can suppress those in the purple and blue boxes. Arrows that stop outside a box apply to all members of the box while those that enter boxes apply only to those mutations they approach closely. Split boxes indicate cases where a single residue suppresses different classes of targets depending on the amino acid substitution, e.g. L176I suppresses G691C while L176F suppresses G680V. Mutations identified in the original cs mutant hunt are written in blue. Many of the residues will transport you to a more in-depth description of the mutation and its genetic, biological and biochemical effects if you click on them.